Nanoparticle diffusion within intestinal mucus: Three-dimensional response analysis dissecting the impact of particle surface charge, size and heterogeneity across polyelectrolyte, pegylated and viral particles

Article ID	Journal	Published Year	Pages	File Type
8412999	European Journal of Pharmaceutics and Biopharmaceutics	2015	9 Pages	PDF

Keywords

MSD Water viscosity Micrometre NP(s)PEGylated nanoparticles Polyallylamine Ad5 IEP MPT μM S.E.M.GIT PAM PAA AFM PDI PLGA PBS +ve Deff G″G′S.D.Adenovirus standard deviation Boltzmann constant Mean Square Displacement standard error of mean Gastrointestinal tract Absolute temperature Second Multiple particle tracking Phase angle poly dispersity index Positive charge Negative charge Effective diffusion coefficient time interval phosphate buffer saline Mucus loss modulus Storage modulus millivolt atomic force microscopy Nanoparticles nanoparticle(s)Polyelectrolyte nanoparticles Nanomètre Isoelectric point Diffusion Virus poly(lactic-co-glycolic acid)polyelectrolyte Polyacrylic Acid kHz

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Nanoparticle diffusion within intestinal mucus: Three-dimensional response analysis dissecting the impact of particle surface charge, size and heterogeneity across polyelectrolyte, pegylated and viral particles

Authors

Muthanna Abdulkarim, Nuria Agulló, Beatrice Cattoz, Peter Griffiths, Andreas Bernkop-Schnürch, Salvador Gómez Borros, Mark Gumbleton,