Multimodal non-linear optical imaging for the investigation of drug nano-/microcrystal-cell interactions

Article ID	Journal	Published Year	Pages	File Type
8413047	European Journal of Pharmaceutics and Biopharmaceutics	2015	11 Pages	PDF

Keywords

ORO HBSS FWHM PFA TPGS THP-1 PMT OPO sHG TPEF HPMC PLM n.a.NEAA RAW 264.7 paliperidone palmitate CARS microscopy d-α-Tocopheryl polyethylene glycol 1000 succinate I.U.HIFBS PAL ROI HEPES PBS DMEM NIR 2-[4-(2-hydroxyethyl)piperazin-1-yl]ethanesulfonic acid H&E l-Glu Dulbecco’s modified Eagle medium Sustained-release Pest EDTA non-essential amino acids l-Glutamine Long-Acting Injectable Non-linear imaging Second harmonic generation numerical aperture Oil red O bright field heat-inactivated fetal bovine serum LAI Phosphate buffered saline two-photon excited fluorescence photomultiplier tube Infrared Near infrared CARS RAW 264.7 macrophages Hank’s balanced salt solution i.m.region of interest Polarized light microscopy optical parametric oscillator haematoxylin and eosin Hydroxypropyl methylcellulose international unit paraformaldehyde Paliperidone coherent anti-Stokes Raman scattering polyethylene glycol PEG

Related Topics

Life Sciences Biochemistry, Genetics and Molecular Biology Biotechnology

Preview

Multimodal non-linear optical imaging for the investigation of drug nano-/microcrystal-cell interactions

Authors

Nicolas Darville, Jukka Saarinen, Antti Isomäki, Leonid Khriachtchev, Dirk Cleeren, Patrick Sterkens, Marjolein van Heerden, Pieter Annaert, Leena Peltonen, Hélder A. Santos, Clare J. Strachan, Guy Van den Mooter,