Article ID Journal Published Year Pages File Type
8414732 European Journal of Pharmaceutics and Biopharmaceutics 2013 10 Pages PDF
Abstract
The current study reports a formulation strategy to produce multi-component spray-dried formulations containing an amorphous matrix for glassy state stabilisation of biomacromolecules by incorporating mannitol, trehalose, glycine and alanine using leucine as an 'encapsulating agent' to assist particle formation.
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Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biotechnology
Preview
The effect of amino acid excipients on morphology and solid-state properties of multi-component spray-dried formulations for pulmonary delivery of biomacromolecules
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