Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8414935 | European Journal of Pharmaceutics and Biopharmaceutics | 2011 | 8 Pages |
Abstract
Fluorescence microscopy photomicrographs of vertical slicing of rat skin. The red color illustrates drugs' skin permeation. Iontophoresis enhanced the delivery of the negative drug, TPPS4, only to the superficial layers of rat skin, while structurally similar but positive TMPyP was transported in higher amounts to deeper skin with homogeneous distribution when the electric current was applied.
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Authors
Guilherme M. Gelfuso, TaÃs Gratieri, Joel G. Souza, José A. Thomazine, Renata F.V. Lopez,