| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8415007 | European Journal of Pharmaceutics and Biopharmaceutics | 2011 | 5 Pages |
Abstract
Haloperidol-loaded polysorbate-coated nanocapsules (H-Nc) showed nanometric size with high efficiency of encapsulation (>95%). When compared to free haloperidol (H-F), H-Nc showed higher therapeutic efficacy on the mania animal model, and reduced extrapyramidal side-effects (catalepsy and dyskinesia).
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Authors
Dalila M. Benvegnú, Raquel C.S. Barcelos, Nardeli Boufleur, PatrÃcia Reckziegel, Camila S. Pase, Aline F. Ourique, Ruy Carlos R. Beck, Marilise E. Bürger,