| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8417769 | Journal of Immunological Methods | 2014 | 5 Pages |
Abstract
Nowadays, enzyme-linked immunosorbent assay (ELISA) based detection of Mycobacterium tuberculosis (M. tuberculosis) antigen triggered interferon-gamma (IFN-g) secretion by blood T cells displays an improved diagnostic value for M. tuberculosis infection. Applications of fluorescence correlation spectroscopy (FCS) have been explored in various subfields of medicine and molecular biology, including detection of a certain biomarker in liquid instead of ELISA. Here, we present a preliminary study of detecting IFN-g using FCS-based technique.
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Authors
Chen Shen, Martin Knapp, Martin Gerald Puchinger, Aamir Shahzad, Erwin Gaubitzer, A Dong Shen, Gottfried Koehler,