Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8418365 | Journal of Immunological Methods | 2012 | 9 Pages |
Abstract
⺠Synovial fluid is a challenging matrix to analyse. ⺠Within-subject experimental design to compare treatment methods. ⺠Hyaluronidase treatment gives better intra-assay precision and signal than diluted or neat samples on the Luminex platform. ⺠These benefits were inconclusive in MSD assays. ⺠We recommend hyaluronidase treatment of synovial fluid for osteoarthritis biomarker research.
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Authors
Chethan Jayadev, Raj Rout, Andrew Price, Philippa Hulley, David Mahoney,