Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8418376 | Journal of Immunological Methods | 2013 | 14 Pages |
Abstract
⺠We developed a novel approach to identifying autoantibodies in RA synovitis. ⺠2183 proteins in human autoantigen library were screened using RA synovia extract. ⺠Plasmacytes producing specific autoantibodies were visualized within the lesion. ⺠The enzyme-labeled antigen method was used for localizing autoantibody production. ⺠Autoantibodies to tripartite motif-containing 21 and F-box only protein 2 were shown.
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Authors
Yasuyoshi Mizutani, Kazuhiro Matsuoka, Hiroyuki Takeda, Kazuya Shiogama, Ken-ichi Inada, Kazue Hayakawa, Harumoto Yamada, Tatsuhiko Miyazaki, Tatsuya Sawasaki, Yaeta Endo, Yutaka Tsutsumi,