Article ID Journal Published Year Pages File Type
8418393 Journal of Immunological Methods 2012 7 Pages PDF
Abstract
► rMHSP65 in combination with IFA induces typical arthritis in rats. ► rMHSP65 could replace mycobacteria in CFA to induce arthritis in rats. ► rMHSP65-IFA induced anti-dsDNA antibody in rats. ► MHSP65 plus IFA could be used to establish animal models of arthritis.
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Life Sciences Biochemistry, Genetics and Molecular Biology Biotechnology
Preview
Recombinant mycobacterial HSP65 in combination with incomplete Freund's adjuvant induced rat arthritis comparable with that induced by complete Freund's adjuvant
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