Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8418428 | Journal of Immunological Methods | 2013 | 7 Pages |
Abstract
⺠69.57% of the rhesus donors had pre-existing anti-AAV8 NAb by assay in vitro. ⺠17 rhesus donors (74.0%) had pre-existing anti-AAV8 neutralization by in vivo NAb assay. ⺠13.04% of samples had anti-AAV8 NAb titers lower than 1:20 by assay in vitro. ⺠NAb assay in vivo is superior to assay in vitro for the sample with low level NAb titer.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biotechnology
Authors
Lan Sun, Lingli Tu, Guangping Gao, Xun Sun, Jiachuan Duan, You Lu,