Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8418536 | Journal of Immunological Methods | 2013 | 4 Pages |
Abstract
⺠DNA vaccines of secreted and intracellular L. chagasi cysteine protease are compared ⺠N-terminal GM-CSFs were fused to the protease to enable secretion of the chimera ⺠Anti-protease antisera from immunized mice were evaluated by Western analysis ⺠Humoral responses were only detected when the protease was intentionally secreted ⺠The effect was attributed to secretion with no augmentation from GM-CSF activity
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biotechnology
Authors
Patrick J. Farrell, Ashwini S. Kucknoor, Kostas Iatrou, Lashitew Gedamu,