Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8418611 | Journal of Immunological Methods | 2012 | 16 Pages |
Abstract
⺠We provide guidelines on how to perform epitope binning on label-free biosensors. ⺠A heterogeneous antigen may lead to contradictory binning results. ⺠We describe a diagnostic assay procedure for identifying antigen heterogeneity. ⺠We recommend a premix format followed by alternative binning formats. ⺠We corroborate binning data with assays that employ native antigen.
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Authors
Yasmina N. Abdiche, Kevin C. Lindquist, Donna M. Stone, Arvind Rajpal, Jaume Pons,