Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8418639 | Journal of Immunological Methods | 2012 | 10 Pages |
Abstract
⺠Quantitative glycan profiles of human IgG and its Fc-Fab portions are reported. ⺠Fab profile including the sialylated glycans is established for the first time. ⺠Fab profile contained highly sialylated and small amount of high-mannose glycans. ⺠Fc specific endoglycosidase S did not cleave the glycans with bisecting GlcNAc. ⺠Simple strategy for quantitative profiling of Fc and Fab glycans is described.
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Authors
Kalyan Rao Anumula,