| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8418713 | Journal of Immunological Methods | 2012 | 16 Pages |
Abstract
⺠HIV-1 mRNA electroporation of PBMC is an efficient method for monitoring of CTL. ⺠We analyzed CTL recognition of autologous HIV-1 strains in HIV-1-infected patients. ⺠Recognition of autologous HIV-1 genes was stronger for 4/8 tested genes. ⺠Use of standard viruses frequently underestimates HIV-1-specific immune response. ⺠CTL escape can lead to a lower recognition of autologous virus (2/8 cases).
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biotechnology
Authors
Jennifer K. Etschel, Angela G. Hückelhoven, Christian Hofmann, Kathrin Zitzelsberger, Katja Maurer, Silke Bergmann, Sandra M. Mueller-Schmucker, Jürgen Wittmann, Bernd M. Spriewald, Jan Dörrie, Niels Schaft, Thomas Harrer,