Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8418714 | Journal of Immunological Methods | 2012 | 8 Pages |
Abstract
⺠Histamine release is more sensitive for the measurement of murine mast cell activation than β-hexosaminidase. ⺠Surface CD200R1 expression can be utilized as a murine mast cell activation marker by flow cytometry. ⺠Histamine release and flow cytometry for CD200R1 can be performed on unpurified peritoneal cells. ⺠These approaches require few cells, so they are ideal for investigating mast cell activation in animal models of disease.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biotechnology
Authors
David Larson, Edward Mitre,