Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8418727 | Journal of Immunological Methods | 2012 | 8 Pages |
Abstract
⺠We evaluated the effect of pre-analytical variables on PrPC detection in blood. ⺠Citrate anticoagulation of blood results in a lower detection of PrPC on monocytes. ⺠The storage of blood leads to a decrease of PrPC detection on most leukocytes. ⺠Platelet satellitism affects PrPC levels detected on many leukocyte populations. ⺠Flow cytometry detection of PrPC is sensitive to storage-generated artifacts.
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Authors
Hana Glier, Karel Holada,