Article ID Journal Published Year Pages File Type
8418727 Journal of Immunological Methods 2012 8 Pages PDF
Abstract
► We evaluated the effect of pre-analytical variables on PrPC detection in blood. ► Citrate anticoagulation of blood results in a lower detection of PrPC on monocytes. ► The storage of blood leads to a decrease of PrPC detection on most leukocytes. ► Platelet satellitism affects PrPC levels detected on many leukocyte populations. ► Flow cytometry detection of PrPC is sensitive to storage-generated artifacts.
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Life Sciences Biochemistry, Genetics and Molecular Biology Biotechnology
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