| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8418759 | Journal of Immunological Methods | 2012 | 9 Pages |
Abstract
⺠Plasma vs. serum and serum collection methods were investigated in biomarker assays. ⺠Autoantibody biomarker assays appear robust to blood type and collection methods. ⺠Inflammation biomarker ELISAs were affected by sample type and handling methods. ⺠Serum samples centrifuged prior to cold-chain shipping were optimal for these assays. ⺠Appropriate sample type and handling methods are important for valid clinical assays.
Keywords
FCSYKL-40EGFVEGF-ASAAVCAM-1CCPMMP-1MMP-3ACRMSDPBSTTNF-RIH2BIL-6histone 2BRheumatoid arthritisAutoantibodyMultiplex immunoassayimmunoglobulin interleukin 6Becton Dickinsonprotein biomarkerserum amyloid Afetal calf serumepidermal growth factorVascular endothelial growth factor AMatrix metalloproteinase 1Matrix metalloproteinase 3Vascular cell adhesion molecule 1C-reactive proteinCRPAmerican College of RheumatologyMeso Scale DiscoveryHuman cartilage glycoprotein 39
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Authors
Xiaoyan Zhao, Ferhan Qureshi, P. Scott Eastman, William C. Manning, Claire Alexander, William H. Robinson, Lyndal K. Hesterberg,