| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8419139 | Journal of Immunological Methods | 2011 | 10 Pages |
Abstract
⺠Phage libraries ideal for rapid isolation of diagnostic antibodies in an emergency. ⺠We compared utility of synthetic scFv and natural Fab libraries for such purposes. ⺠All antibodies from Fab library could be rapidly expressed as full-length IgG. ⺠Majority of scFv library antibodies carry amber stops or CDR glycosylations. ⺠Screening Fab library therefore preferred method for rapid antibody development.
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Authors
Conrad E.Z. Chan, Annie H.Y. Chan, Angeline P.C. Lim, Brendon J. Hanson,