Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8419166 | Journal of Immunological Methods | 2011 | 16 Pages |
Abstract
⺠Developed a method to identify T cell epitopes, critical tools for immunology. ⺠Uses bacterial expression libraries and solid-phase antigen delivery. ⺠Identified MHC class I restricted altered epitopes with super-agonist activities. ⺠Showed feasibility of screening expression library constructed from F. tularensis. ⺠Identified epitopes in Francisella pathogenicity proteins using new Gateway vector.
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Authors
Michael D. Valentino, C. Siddiq Abdul-Alim, Zachary J. Maben, Denise Skrombolas, Lucinda L. Hensley, Thomas H. Kawula, Michelle Dziejman, Edith M. Lord, Jeffrey A. Frelinger, John G. Frelinger,