Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8419254 | Journal of Immunological Methods | 2011 | 10 Pages |
Abstract
⺠The endocannabinoid 2-AG is a major residual lipid in commercial FBS. ⺠2-AG in FBS can induce significant cellular activation of primary monocytes/macrophages and increase RANKL-stimulated osteoclastogenesis. ⺠LPS-stimulated U937 cells show differential IL-6 expression depending on FBS batch. ⺠Polymyxin B beads bind to and selectively remove 2-AG.
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Authors
Janine Marazzi, Jonas Kleyer, Juan Manuel Viveros Paredes, Jürg Gertsch,