Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8419269 | Journal of Immunological Methods | 2011 | 11 Pages |
Abstract
⺠TNFα responsive reporter cells can quantify TNFα activity within 2 hours. ⺠Reporter cells can quantify anti-TNFα drug activity in human serum. ⺠Reporter cells can quantify neutralizing antibodies to anti-TNFα drugs in serum. ⺠Results independent of sample cytotoxicity or serum matrix effects.
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Authors
Christophe Lallemand, Nadia Kavrochorianou, Casper Steenholdt, Klaus Bendtzen, Mark A. Ainsworth, Jean-Francois Meritet, Brigitte Blanchard, Pierre Lebon, Peter Taylor, Peter Charles, Saba Alzabin, Michael G. Tovey,