| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8419649 | Journal of Immunological Methods | 2010 | 9 Pages |
Abstract
Flow cytometry offers a means to quickly screen patients for XLP. Flow cytometry can be used to measure lymphocyte SAP or XIAP protein expression, and can also be used to observe lymphocyte phenotypes and functional defects that are unique to XLP. This review will give a brief overview of the clinical manifestations and molecular basis of SAP deficiency and XIAP deficiency, and will focus on the use of flow cytometry for diagnosis of XLP.
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Authors
Rebecca A. Marsh, Jack J. Bleesing, Alexandra H. Filipovich,