| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8429132 | Best Practice & Research Clinical Haematology | 2017 | 10 Pages |
Abstract
The sheer diversity of HLA alleles makes the probability of finding matched unrelated donors for patients requiring hematopoietic cell transplantation (HCT) a complex situation. New evidence suggests that mismatching at certain HLA loci may provide a greater benefit in terms of graft-versus-leukemia effect than other mismatches when HLA-matched donors are not available. This review summarizes the current understanding of HLA matching requirements for unrelated donor HCT.
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Authors
Effie W. Petersdorf,