Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8429354 | Biochimica et Biophysica Acta (BBA) - Reviews on Cancer | 2018 | 11 Pages |
Abstract
In the last decade, experimental evidences have shown that PTX3 may exert a significant impact also on different aspects of cancer biology, including tumor onset, angiogenesis, metastatic dissemination and immune-modulation. However, it remains unclear whether PTX3 acts as a good cop or bad cop in cancer. In this review, we will summarize and discuss the scientific literature data focusing on the role of PTX3 in experimental and human tumors, including its putative translational implications.
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Authors
Arianna Giacomini, Gaia Cristina Ghedini, Marco Presta, Roberto Ronca,