The driver and passenger effects of isocitrate dehydrogenase 1 and 2 mutations in oncogenesis and survival prolongation

Article ID	Journal	Published Year	Pages	File Type
8429426	Biochimica et Biophysica Acta (BBA) - Reviews on Cancer	2014	58 Pages	PDF

Keywords

O6-methylguanine-DNA methyltransferase JmjC KDM EGLN TET2 BRD4 d-2-hydroxyglutarate d-2HG αKG G6PDH TMZ IDH ECM Bcat1 MGMT MDS MPN GSH NADPH ICC IDH2 AML IDH1 ROS α-ketoglutarate Isocitrate dehydrogenase ionizing radiation Temozolomide myelodysplastic syndrome Vascular endothelial growth factor Vascular Endothelial Growth Factor (VEGF)acute myeloid leukemia lysine demethylase Extracellular matrix Myeloproliferative neoplasms Bromodomain-containing protein 4 SNP Intrahepatic cholangiocarcinoma Glutathione (reduced)glucose-6-phosphate dehydrogenase Glioma Reactive oxygen species

Related Topics

Life Sciences Biochemistry, Genetics and Molecular Biology Cancer Research

The driver and passenger effects of isocitrate dehydrogenase 1 and 2 mutations in oncogenesis and survival prolongation

Authors

Remco J. Molenaar, Tomas Radivoyevitch, Jaroslaw P. Maciejewski, Cornelis J.F. van Noorden, Fonnet E. Bleeker,