| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8429987 | Biology of Blood and Marrow Transplantation | 2018 | 33 Pages |
Abstract
- Missing KIR2DL1 ligands were associated with a lower relapse incidence in HLA-matched HSCT for AML or CML, but not for low-grade MDS or ALL.
- HLA-C1/C1 recipients with AML or CML showed an advantage irrespective of donor relation, preparative regimen, occurrence of acute GVHD, or CMV reactivation.
- This advantage of HLA-C1/C1 over HLA-C1/C2 was most pronounced in T cell- depleted HSCT and in childrenâage <15 years.
Keywords
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Authors
Nobuyoshi Arima, Junya Kanda, Junji Tanaka, Toshio Yabe, Yasuo Morishima, Sung-Won Kim, Yuho Najima, Yukiyasu Ozawa, Tetsuya Eto, Heiwa Kanamori, Takehiko Mori, Naoki Kobayashi, Tadakazu Kondo, Hirohisa Nakamae, Naoyuki Uchida, Masami Inoue,