Common variants in the obesity-associated genes FTO and MC4R are not associated with risk of colorectal cancer

Article ID	Journal	Published Year	Pages	File Type
8433079	Cancer Epidemiology	2016	4 Pages	PDF

Abstract

We found no evidence that individual variants in or near the obesity-related genes FTO and MC4R are associated with risk of colorectal cancer.

Keywords

CCFR MAF MC4R PCA genetic variants FTO Colorectal cancer body mass index BMI confidence interval minor allele frequency Obesity Genome-wide association study Case-control study GWAS odds ratio Single nucleotide polymorphism SNP Melanocortin-4 receptor

Related Topics

Life Sciences Biochemistry, Genetics and Molecular Biology Cancer Research

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Common variants in the obesity-associated genes FTO and MC4R are not associated with risk of colorectal cancer

Authors

Baiyu Yang, Aaron P. Thrift, Jane C. Figueiredo, Mark A. Jenkins, Fredrick R. Schumacher, David V. Conti, Yi Lin, Aung Ko Win, Paul J. Limburg, Sonja I. Berndt, Hermann Brenner, Andrew T. Chan, Jenny Chang-Claude, Michael Hoffmeister, Thomas J. Hudson,