| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8434097 | Cancer Letters | 2018 | 43 Pages |
Abstract
Currently, momentum is gathering towards the development of systemically-deliverable mutants that are able to overcome anti-viral host immune responses, erythrocyte binding and hepatic uptake, to promote elimination of primary and metastatic lesions. This review will cover the key components of pancreatic cancer oncogenesis; novel oncolytic adenoviruses; clinical trials; and the current progress in overcoming the challenges of systemic delivery.
Keywords
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Authors
Callum Baird Nattress, Gunnel Halldén,