| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8435706 | Cancer Letters | 2013 | 8 Pages |
Abstract
⺠Targeted bisulfite sequencing is emerging as a powerful approach for genome-wide DNA methylation analysis. ⺠A variety of sequence capture methods have been developed for targeted bisulfite sequencing. ⺠Software programs are available for high-throughput primers/probes design and downstream bioinformatics analysis. ⺠Application of targeted bisulfite sequencing approaches can reduce costs and improve the sensitivity and accuracy of methylation detection.
Keywords
CGIBSPPAMLMeDIPMeDIP-SeqMSPICFMBDMDSCOBRAMCASHSNGSDMHMethylated DNA immunoprecipitationmethylation specific PCRNext-generation sequencingCpG islandmethyl-binding domainDREAMembryonic stemMyelodysplastic syndromesMatrix-assisted laser desorption/ionization-time of flight mass spectrometryacute myeloid leukemiaMALDI-TOF MSDNA methylationMIRApolymerase chain reactionPCRHeLP
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Authors
Eun-Joon Lee, Junfeng Luo, James M. Wilson, Huidong Shi,