| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8438942 | EBioMedicine | 2016 | 10 Pages |
Abstract
We have identified that SHOX2 expression or methylation are potent independent prognostic indicators for predicting LGG patient survival, and have potential to identify an important subset of LGG patients with IDHwt status with significantly better overall survival. The combination of IDH or other relevant markers with SHOX2 identified LGG subsets with significantly different survival outcomes, and further understanding of these subsets may benefit therapeutic target identification and therapy selections for glioma patients.
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Authors
Yu-An Zhang, Yunyun Zhou, Xin Luo, Kai Song, Xiaotu Ma, Adwait Sathe, Luc Girard, Guanghua Xiao, Adi F Gazdar,