| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8439191 | EBioMedicine | 2016 | 8 Pages |
Abstract
A single course of PQ significantly reduces gametocyte carriage in malaria-infected asymptomatic, G6PD-normal individuals without increasing the risk of clinical anemia. The limited number of successful mosquito infections suggests that post-treatment transmission potential in this asymptomatic population is low.
Keywords
QT-NASBACYP2D6IQRMRCACTG6PDDHAPEfficacystandard deviationanalysis of varianceANOVAartemisinin-based combination therapycytochrome P450 2D6Medical Research CouncilInfectivityAsymptomatic infectionconfidence intervalMalariamean differencehazards ratiointerquartile ratioPrimaquinePlasmodium falciparumrandomized trialglucose-6-phosphate dehydrogenase
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Authors
Joseph Okebe, Teun Bousema, Muna Affara, Gian Luca Di Tanna, Edgard Dabira, Abdoulaye Gaye, Frank Sanya-Isijola, Henry Badji, Simon Correa, Davis Nwakanma, Jean-Pierre Van Geertruyden, Chris Drakeley, Umberto D'Alessandro,