Article ID Journal Published Year Pages File Type
8439532 European Journal of Cancer 2018 5 Pages PDF
Abstract

- Microsatellite instability is considered as an early event in carcinogenesis of colorectal deficient DNA mismatch repair system without tumoural heterogeneity
- Here we have described a case of microsatellite instability presenting intra- and inter-tumoural heterogeneity
- Some precautions must be taken in microsatellite instability testing and immunochemistry of DNA mismatch repair proteins, especially before treatment with immune checkpoint inhibitors
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Cancer Research
Authors
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