Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8441243 | European Journal of Cancer | 2016 | 8 Pages |
Abstract
Chronically injured gastric mucosa increases lipoperoxidative events and cell proliferation. In the adenocarcinoma, cell proliferation was further enhanced, oxidant stress decreased which seemed to be linked to NOX1, MDC1 and cyclin D1 over-expression, but with a lower NOXs activity leading a 'low tone' of ROS formation. Therefore, our results could be useful for early detection and treatment of gastric adenocarcinoma.
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Authors
Eduardo E. Montalvo-Javé, Marisela OlguÃn-MartÃnez, Diego R. Hernández-Espinosa, Lourdes Sánchez-Sevilla, Edgar Mendieta-Condado, Martha L. Contreras-Zentella, Luis F. Oñate-Ocaña, Tomás Escalante-Tatersfield, AgustÃn Echegaray-Donde,