Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8443794 | European Journal of Cancer | 2014 | 10 Pages |
Abstract
The treatment with bevacizumab, cetuximab and panitumumab is mainly considered to be not cost-effective in patients with mCRC. However, testing for Kirsten ras oncogene (KRAS) mutation prior to the treatment with cetuximab or panitumumab is found to be clearly cost-effective compared to no testing. Future research should focus on the CE of first-line treatment with cetuximab or panitumumab and studies on upcoming agents like regorafenib and aflibercept.
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Authors
A. Lange, A. Prenzler, M. Frank, M. Kirstein, A. Vogel, J.M. von der Schulenburg,