| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8443877 | European Journal of Cancer | 2013 | 11 Pages |
Abstract
Our findings suggest a tubal origin of BTs through transitional metaplasia and Walthard cell nests, based on their anatomic proximity, similar IHC profile and the presence of cilia. In addition, we hypothesise a role of androgenic stimulation in the pathogenesis of BT, based on the IHC staining pattern of calretinin, inhibin and steroidogenic factor 1 expressed in the luteinised stromal cells surrounding the epithelial nests of the tumours, and AKR1C3 and androgen receptor expressed in both the epithelial and stromal components.
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Authors
Elisabetta Kuhn, Ayse Ayhan, Ie-Ming Shih, Jeffrey D. Seidman, Robert J. Kurman,