Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8444618 | European Journal of Cancer | 2010 | 12 Pages |
Abstract
Our findings indicate that miR-17-5p/20a promote gastric cancer cell proliferation and inhibit cell apoptosis via post-transcriptional modulation of p21 and TP53INP1. They may be promising therapeutic markers for gastric cancer. MDM2 contributes to miR-17-5p/20a function and inhibition of p21 in gastric cancer, and may be a novel mechanism underlying the oncogenic roles of miR-17-5p/20a.
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Authors
Mei Wang, Hongbing Gu, Hui Qian, Wei Zhu, Chonghui Zhao, Xu Zhang, Yang Tao, Ling Zhang, Wenrong Xu,