Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8444991 | European Journal of Cancer | 2013 | 11 Pages |
Abstract
The combination chemotherapy as compared to gemcitabine alone significantly improves OS in advanced pancreatic cancer (APC). However, this advantage is marginal whereas the treatment-related toxicity is increased, suggesting the use of gemcitabine-based combination regimens only in selected patient populations. New prospective trials, based on translational approaches and innovative validated biomarkers, are eagerly awaited on this topic.
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Authors
Domenico Ciliberto, Cirino Botta, Pierpaolo Correale, Marco Rossi, Michele Caraglia, Pierfrancesco Tassone, Pierosandro Tagliaferri,