Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8445063 | European Journal of Cancer | 2013 | 10 Pages |
Abstract
These data demonstrate that IRF-1 is up-regulated by CDDP in ovarian cancer cells and might limit the cell response to CDDP, likely by inhibiting cell proliferation. Data suggest that IRF-1 induction might interfere with the effectiveness of combination therapy with platinum drugs and cytokines.
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Authors
Simona Pavan, Martina Olivero, Davide Corà , Maria Flavia Di Renzo,