| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8445225 | European Journal of Cancer | 2013 | 5 Pages |
Abstract
We describe the striking and unexpected evolution of 10 patients with de novo multiple myeloma treated with novel-agent based induction therapy, who displayed a dissociated evolution characterised by an apparent good response contrasting with the concomitant development of aggressive non-secreting plasmocytomas immediately before, or just after, autologous stem cell transplantation. Patients did not respond to salvage therapies. Eight of them died from progression less than 12Â months after diagnosis. This unusual evolution in the era of novel agents warrants further scrutiny.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Cancer Research
Authors
Etienne Crickx, Sebastian Wittnebel, Florence Pasquier, Alina Danu, Jean-Henri Bourhis, Vincent Ribrag, Francois Boué, Corinne Miceli, Xavier Mariette, Philippe Moreau, Stéphane de Botton, David Ghez,