Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8445396 | European Journal of Cancer | 2013 | 10 Pages |
Abstract
A low prevalence of occult invasive cancer (1.1%) was found in young asymptomatic, screen-negative women at increased ovarian cancer risk undergoing RRSO. This study adds to the advice to perform RRSO in BRCA1-carriers before the age of 40. Our findings support the hypothesis of the fallopian tube as the primary site of origin of pelvic high-grade serous cancer.
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Authors
Welmoed Reitsma, Geertruida H. de Bock, Jan C. Oosterwijk, Joost Bart, Harry Hollema, Marian J.E. Mourits,