Article ID Journal Published Year Pages File Type
8446119 European Journal of Cancer 2012 8 Pages PDF
Abstract
This meta-analysis does not support the hypothesis that infusion of Ca/Mg reduces the occurrence of neurotoxicity in oxaliplatin-treated patients with colorectal cancer measuring with NCE-CTC criteria. On the other hand, our results support the hypothesis that administrations of Ca/Mg do not impair the efficacy of oxaliplatin-based chemotherapy. However, large-scale randomised, controlled clinical trials will be required to confirm these hypotheses.
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Life Sciences Biochemistry, Genetics and Molecular Biology Cancer Research
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