| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8446215 | European Journal of Cancer | 2012 | 8 Pages |
Abstract
Aberrant staining of β-catenin in paediatric desmoids helps to identify children at risk for FAP. We recommend to screen paediatric desmoid tumours for nuclear localisation of β-catenin and consequently for CTNNB1 mutations. For patients with nuclear β-catenin expression and no CTNNB1 mutations, APC mutation analysis should be offered after genetic counselling.
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Authors
Anna A. Kattentidt Mouravieva, Ina R.R. Geurts-Giele, Ronald R. de Krijger, Max M. van Noesel, Cees P. van de Ven, Ans M.W. van den Ouweland, Joan N.R. Kromosoeto, Winand N.M. Dinjens, Hendrikus J. Dubbink, Ron Smits, Anja Wagner,