Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8446874 | European Journal of Cancer | 2012 | 10 Pages |
Abstract
Temsirolimus administered weekly at the dose of 75Â mg/m2 did not meet the primary objective efficacy threshold in children with high-grade glioma, neuroblastoma or rhabdomyosarcoma; however, meaningful prolonged stable disease merits further evaluation in combination therapy.
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Authors
Birgit Geoerger, Mark W. Kieran, Stephan Grupp, Danuta Perek, Jill Clancy, Mizue Krygowski, Revathi Ananthakrishnan, Joseph P. Boni, Anna Berkenblit, Sheri L. Spunt,