| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8447626 | European Journal of Cancer | 2011 | 9 Pages |
Abstract
L19-SIP shows a time and blood-flow dependent microvascular biodistribution process with angiogenic sprouts as preferential binding sites followed by secondary extravasation of the antibody. Microvascular biodistribution is enhanced in anti-angiogenic-therapy resistant tumour vessels.
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Authors
Marcus Czabanka, Güliz Parmaksiz, Simon H. Bayerl, Melina Nieminen, Eveline Trachsel, Hans D. Menssen, Ralf Erber, Dario Neri, Peter Vajkoczy,