Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8448451 | European Journal of Cancer | 2009 | 9 Pages |
Abstract
Frequent silencing of MLH1 and downregulation of MMR target genes, such as MRE11 and MBD4, characterised MSI tumours. The downregulation of SMUG1 was also a typical feature of these tumours. The DNA repair gene expression profile of gastric cancer with MSI is of relevance for therapy response.
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Authors
Mariarosaria D'Errico, Emanuele de Rinaldis, Monica F. Blasi, Valentina Viti, Mario Falchetti, Angelo Calcagnile, Francesco Sera, Calogero Saieva, Laura Ottini, Domenico Palli, Fabio Palombo, Alessandro Giuliani, Eugenia Dogliotti,