Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8451641 | Experimental Cell Research | 2018 | 27 Pages |
Abstract
In conclusion, the findings demonstrated that mutated K-ras promotes cathepsin L expression and plays a pivotal role in EMT of human lung cancer. The regulatory effect of IR-induced cathepsin L on lung cancer invasion and migration was partially attributed to the Cathepsin L /CUX1-mediated EMT signaling pathway. This study will provide cathepsin L as a potential target for tumor therapy.
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Authors
Long Wang, Yifan Zhao, Yajie Xiong, Wenjuan Wang, Yao Fei, Caihong Tan, Zhongqin Liang,