| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8452070 | Experimental Cell Research | 2017 | 44 Pages |
Abstract
Differential cysteine-supply systems between the primary mouse hepatocytes and Hepa 1-6 cells under conventional or Cys/Met-free culture. Met; Methionine, Hcy; Homocysteine, Cst; Cystathionine, Cys; Cysteine, Thr; Threonine, Glu; Glutamate, 2OB; 2-Oxo-butyric acid, 2AB; 2-Amino-butyric acid, GSH; Glutathione, OPT; Ophthalmic acid, γGCS; γ-Glutamylcysteine synthetase, GS; Glutathione synthetase; NAAT; neutral amino acid transporter247
Keywords
N-ethylmaleimideLC-MSCysOPTCBSHRPmTORCTNSSAMGSHPPG2MeH2DCF-DACSExCT2ABγGCSPBS2-mercaptoethanolcystathionine γ-lyaseROSγ-glutamylcysteine synthetaseASTAutophagyS-adenosylmethionine2-aminobutyric acidOphthalmic acidaspartate transaminaseCysteinecystathionine β-synthaseCystineCystinosinLiquid chromatography-mass spectrometryMEMMethioninePhosphate-buffered salineMETwild typemammalian target of rapamycinHorseradish peroxidasePropargylglycineGluGlutathioneglutathione reductaseglutathione synthetaseglutamateGlyGlycineReactive oxygen species
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Authors
Jaeyong Lee, Eun Sil Kang, Sho Kobayashi, Takujiro Homma, Hideyo Sato, Han Geuk Seo, Junichi Fujii,