| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8452109 | Experimental Cell Research | 2017 | 28 Pages |
Abstract
SAHA is a potent sensitizer of TRAIL responses in both TRAIL sensitive and resistant cell lines, in both suspension and 3D culture, however SAHA did not sensitise TRAIL-sensitive cell populations that had been selected for TRAIL-resistance from initially TRAIL-sensitive populations. SAHA may increase TRAIL sensitivity in insensitive cells, but not in cells that have specifically been selected for acquired TRAIL-resistance.
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Authors
A. Arhoma, A.D. Chantry, S.L. Haywood-Small, N.A. Cross,