Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8452586 | Experimental Hematology | 2018 | 23 Pages |
Abstract
- Intrinsic and extrinsic bone morphogenic protein (BMP) signaling alterations promote cancer stem cell (CSC) features.
- Under treatment, BMP alterations evolve independently of the oncogene.
- Leukemic and nonleukemic BMP deregulations drive resistance and constitute therapeutic targets.
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Authors
Florence Zylbersztejn, Mario Flores-Violante, Thibault Voeltzel, Franck-Emmanuel Nicolini, Sylvain Lefort, Véronique Maguer-Satta,