| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8452702 | Experimental Hematology | 2018 | 33 Pages |
Abstract
- H3K27 and selected H3K9 demethylases show upregulated expression in human AML.
- Elevated KDM6 expression correlates with reduced global H3K27Me3 in AML.
- KDM6 inhibition with GSKJ4 reduces AML cell survival.
- Combination with KDM4 inhibition increases efficacy of GSKJ4.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Cancer Research
Authors
Liberalis Debraj Boila, Shankha Subhra Chatterjee, Debasis Banerjee, Amitava Sengupta,